Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis By
نویسنده
چکیده
Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condition with a raised serum calcium and symptoms suggestive of idiopathic hypercalcaemia has since been described in two case reports (Clay, 1956; Martin and Steven, 1957). No explanation for this association has yet been offered. In this paper a further case of neonatal subcutaneous fat necrosis is described in which a raised serum calcium was found, together with the symptoms of hypercalcaemia. The significance of hypercalcaemia in subcutaneous fat necrosis is discussed.
منابع مشابه
Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis.
Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...
متن کاملSubcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcification.
Subcutaneous fat necrosis of the newborn (SCFN) is a very rare disorder, which can be complicated by hypercalcaemia and thrombocytopenia. The case is presented of an infant with SCFN and symptomatic hypercalcaemia, who developed calcifications in the liver, the inferior vena cava, and the atrial septum of the heart. The hypercalcaemia was treated with hyperhydration, frusemide, glucocorticoids,...
متن کاملSubcutaneous fat necrosis of the newborn following hypothermia and complicated by pain and hypercalcaemia.
A female infant was delivered at term with complications of severe meconium aspiration and birth asphyxia. Surface cooling was performed in the first 24 hours as part of the management of her birth asphyxia. Woody erythema was noted at 24 hours, followed by the formation of red-purple nodules on the 6th day. Clinical findings in the first 24 hours were suggestive of cold panniculitis. However, ...
متن کاملFrequency and aetiology of hypercalcaemia.
BACKGROUND Hypercalcaemia is rare in children and may present with characteristic signs/symptoms or coincidentally following investigations for a variety of non-specific conditions. The aetiologies of childhood hypercalcaemia are diverse. Untreated sustained hypercalcaemia has serious clinical consequences. However there is limited data regarding the true frequency and aetiologies of childhood ...
متن کاملZoledronic acid for neonatal subcutaneous fat necrosis
Subcutaneous fat necrosis (SFN) in infants producing severe hypercalcemia is a life-threatening emergency. Pathophysiology may include enhanced gastrointestinal calcium absorption and bone resorption. We treated an infant with SFN and serum calcium of 15 mg/dL with prednisolone and low-dose zoledronic acid. Serum calcium promptly normalized without rebound hypocalcemia, and redosing of zoledron...
متن کامل